1) Наднорменото тегло

Счита се, че наднорменото тегло и по-специално излишното тегло около талията, е основна причина за инсулинова резистентност. Причината за това е, че мазнините около органите имат роля в развитието на хронични възпаления чрез комплексни механизми, които с времето могат да доведат до тежки последствия за здравето.

2) Обездвижването (физическата неактивност)

Много изследвания показват, че липсата на физическа активност се свързва с инсулиновата резистентност, често водеща до диабет тип 2. Същите тези изследвания сочат, че след упражнения мускулите стават по-чувствителни към инсулина, което води до спиране развитието на инсулинова резистентност и редуциране на нивата на кръвната глюкоза. Освен това упражненията спомагат за абсорбиране на повече глюкоза от мускулите без да е нужно допълнително количество инсулин, а колкото повече мускули има човек, толкова повече глюкоза ще бъде изгаряна, за да се контролират нивата ѝ в кръвта.

3) Генетични и други причини

Други причини за инсулиновата резистентност са генетичната предразположеност, определени заболявания, употребата на стероиди и някои лекарства, възрастта, проблеми със съня (като сънна апнея) и пушенето.

Източници:

[1] Водят ли въглехидратите към инсулинова резистентност? Strongby.science, <https://medium.com/@strongbysciencebulgaria/8carbsandinsulinresistance-a8b345327c2a>

[2] Prediabetes & Insulin Resistance. National Institute of Diabetes and Digestive and Kidney Diseases. Retrieved from niddk.nih.gov, <https://www.niddk.nih.gov/health-information/diabetes/overview/what-is-diabetes/prediabetes-insulin-resistance>

[3] Hardy, O., T. et. al. What causes insulin resistance underlying obesity? Current Opinion in Endocrinology, Diabetes and Obesity, 2014, <https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038351/>


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