Скелетната мускулатура бива едновременно “изграждана” (чрез протеинов синтез) и “разграждана” (чрез протеинов разпад). Причината за този протеинов “метаболизъм” е изхвърляне на старите протеини и замяната им с нови [1]. Процесите на мускулно- протеиновия синтез и (МПС) и мускулно-протеиновия разпад (МПР) определят промяната в мускулната маса или нетния протеинов баланс (НПБ). За изграждане на мускулна маса НПБ трябва да е положителен, защото тогава МПС ще надвишава МПР. Когато МПР е по-голям от МПС, тогава се наблюдава намаляване на мускулната маса: [2]

% НПБ (нетен протеинов баланс) = МПС (мускулно-протеинов синтез) – МПР (мускулно-протеинов разпад)

👩‍⚕Една от най-популярните добавки в днешно време са аминокиселините с разклонена верига BCAA, а продажбите на тази добавка възлизат на милиони долари [3]. Те са широко рекламирани като добавка, която увеличава мускулно-протеиновия синтез, намалява мускулно-протеиновия разпад и увеличава мускулната маса [1]. Kонцепцията за стимулиране на мускулен растеж, в резултат от прием на тази добавка, се проповядва от повече от 35 години. Информацията, която подкрепя тази хипотеза, се базира единствено на изследвания с мишки. Тези изследвания обаче имат ограничено значение по отношение на ефекта при хората [3].

Оказва се, че при хората BCAA добавките активират мускулно-протеинов синтез, но ефектът е краткотраен. Причината за това е, че BCAA добавките не предоставят всичките незаменими аминокиселини, които са необходими, за да се осъществи значително увеличение на мускулно-протеиновия синтез (МПС) [1]. За сметка на това тези аминокиселини се добиват от разпад на мускулна тъкан (МПР). Около 70% от всички незаменими аминокиселини, генерирани чрез мускулен разпад, отново се реинкорпорират в мускулен протеин. А тъй като BCAA добавките увеличават ефективността на този процес и подтискат МПР, дори още по-малко незаменими аминокиселини остават налични за МПС [1].Това прави невъзможно постигане на значително увеличение на МПС и положителен нетен протеинов баланс (МПС > МПР), което предотвратява възможността за изграждането на нова мускулна тъкан.

☝Изводи [1,3,4,5]:

  • BCAA добавките могат да стимулират мускулно-протеинов синтез, но ако не са налични всички нужни за това аминокиселини ефектът ще бъде преходен (краткотраен);
  • Твърденията на производителите на хранителни добавки, че BCAA сами по-себе си увеличават мускулната маса, не са подкрепени с доказателства. Те са неверни и физиологично неосъществими;
  • Консумиране на пълноценен протеин ще бъде много по-ефективна стратегия за стимулиране на МПС (мускулно-протеинов синтез), което ще доведе до положителен НПБ (нетен протеинов баланс) и съответстващо увеличение на мускулната маса.

📚Източници: 

[1] “BCAA и мускулно-протеиновия синтез” Инфографично видео на Guru Performance Institute, <https://bit.ly/2wt83eS>

[2] “Протеинът от храната води до усилване на анаболизма при млади трениращи мъже”. Journal of the American College of Nutrition, 2005, <https://bit.ly/2wq7mmK>

[3] “BCAA и мускулния протеинов синтез: мит или реалност?” Ревю на Международното общество по спортно хранене относно ефективността на BCAA добавките, <https://bit.ly/2iqETJQ>

[4] “BCAA добавките не притежават анаболен ефект”. Статия на Joseph Agu. FB/Josephagunutrition, <https://bit.ly/2NgoNNL>

[5] “BCAA добавки за бодибилдъри: Само науката”. Elitenutritioncoaching.com, <https://bit.ly/2PE9OPp>

Categories: Supplements

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(read the complete review of OJOsoft MP4 to MP3 Converter…)

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Making digital copies of your favourite movies and music might seem easy enough, but how exactly does the company that produced a movie manage to offer its consumers complete ownership of that movie? The same question can be asked about other types of multimedia content, including photographs and photographs. So how do you take a photograph and turn it into a permanent and efficient image https://waappitalk.com/upload/files/2022/06/dga7xD2uxO2PqKKxo48a_06_7fbd3131f21b3c26986b068f86f726c4_file.pdf
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haylleon · June 8, 2022 at 7:39 pm

and is abstracted as follows. We have a population of prey $x(t)$ at time $t$, which obeys the following ODE
$$\frac{dx(t)}{dt} = p_0 – rx(t) – x(t)\int_{0}^{x(t)} \frac{dy(t)}{x(t)},$$
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The planet earth shows all of the features and the environment in which butterflies live in. There are seven different parts, thousands of butterflies, and you can take a virtual trip with them to a place of your choice.
As soon as you start up this program, you will see the option of the date and the time.

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express an opinion for the purpose of forming it

4
Fed.R.Evid. 803, adopted in 1980, provides, in pertinent part:
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sanddei · June 8, 2022 at 8:56 pm

Julia Set Plotter
Julia Set Plotter, similarly to its namesake, is an application for plotting the Julia fractal. It will provide a number of features that can be useful for those who prefer to use this fractal, that will include image resizing, color selection, animation, save rendered images, save videos and even a number of extra features that allow one to create AVI clips.
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In the following example, are show that, There are fileA.txt and fileB.txt, thus showing the caller information, the number is the same, but with add on the end.

Q:

What is the extention for.ics files?

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gnekeil · June 8, 2022 at 9:47 pm

From the HD Graphics Driver site: “This download provides the video driver Graphics adapter that is used to provide video output capability to a newly installed copy of Microsoft Windows Vista. Download the.zip file to extract the contents to a location on your hard drive such as “C” drives. Access the video driver distribution file that matches the location where you are saving it. ”

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isatak · June 8, 2022 at 10:52 pm

You can download RegCool for Windows here.Dental the Navigator

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bernwon · June 9, 2022 at 2:54 am

Download your code from GitHub. The YAML file is at codemock_de.yaml.
Deploy your applications!

YAML Beans is an open-source Java library released under the Apache Software License v 2.0
You should also read the README and LICENSE files for more info and licensing.
Just for the record, I’m the lead developer.

A:

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sedtanc · June 9, 2022 at 9:12 am

Malware from Easter-based Russian cybercrooks doesn’t always consist of viruses. Just as your phone company can spot malware spreading through your devices with call traffic or phone text messages, your broadband provider may be watching out for malware arriving through the internet.
Computerworld reports that a Moscow-based company called New Resolution is using the ISP-level infrastructure to intercept traffic from infected devices, extract intel, and then shut down the associated network connection remotely. The company claims that it can hand https://unmown.com/upload/files/2022/06/lwdJF8qH2Uv2rvTvHFxE_06_b63fd0cad2264669aa25373e205dae7e_file.pdf
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